Modafinil for Clozapine-Treated Schizophrenia Patients
نویسندگان
چکیده
منابع مشابه
Myoclonus as an indicator of infection in patients with schizophrenia treated with clozapine.
Clozapine is the treatment of choice for refractory schizophrenia. However, a retrospective analysis indicated that death was a common cause of ceasing clozapine treatment. In another study that investigated the reasons for discontinuing clozapine, pneumonia was the primary cause of death in about 24% of patients. Therefore, the relation between the risk of pneumonia and clozapine has raised cl...
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The aim of our study was to detect changes in the distribution of electrical brain activity in schizophrenic patients who were antipsychotic naive and those who received treatment with clozapine, olanzapine or risperidone. We included 41 subjects with schizophrenia (antipsychotic naive = 11; clozapine = 8; olanzapine = 10; risperidone = 12) and 20 healthy controls. Low-resolution brain electrom...
متن کاملCerebroventricular clozapine would be a viable treatment modality for clozapine-dependent schizophrenia patients with neutropenia.
The atypical antipsychotic clozapine is very effective for treatment of schizophrenia, but it causes agranulocytosis requiring drug cessation in up to 2% of cases. There has been some success rechallenging with clozapine at a later date or giving granulocyte colony stimulating factor or lithium while continuing clozapine. However, there are still some patients for whom these strategies do not w...
متن کاملModafinil and armodafinil in schizophrenia.
What Might Be the Positive Spin-Offs Associated With Modafinil or Armodafinil Use in This Patient? Racemic modafinil and its R-isomer armodafinil are approved treatments for the excessive daytime drowsiness associated with narcolepsy, shift work, and obstructive sleep apnea1; therefore, either of these drugs could benefit Mr P. In schizophrenia, modafinil and armodafinil have been prescribed, s...
متن کاملClozapine alone versus clozapine and risperidone for refractory schizophrenia.
BACKGROUND The treatment of schizophrenia with multiple antipsychotic drugs is common, but the benefits and risks are not known. METHODS In a randomized, double-blind study, we evaluated patients with schizophrenia and a poor response to treatment with clozapine. The patients continued to take clozapine and were randomly assigned to receive eight weeks of daily augmentation with 3 mg of rispe...
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ژورنال
عنوان ژورنال: The Journal of Clinical Psychiatry
سال: 2009
ISSN: 0160-6689
DOI: 10.4088/jcp.08m04683